From Cells to Insight
End-to-End 3D Neural Screening Services with RealBrain® Technology
Accelerate Preclinical Neuroscience Drug Discovery
Predictive. Scalable. Human-relevant.
Our proprietary 3D neural models—ARTIBrain™ and ADBrain™—deliver validated platforms for efficacy, safety, and mechanistic studies.
Designed for high-throughput applications, they produce consistent, translatable data to support confident decision-making.
Disease-Relevant Human Brain Models
ARTIBrain™ – Healthy Adult Brain Model
Captures baseline neural complexity for toxicity profiling and control comparisons.
ADBrain™ – Alzheimer’s Disease Model
Recapitulates amyloid aggregation, tau pathology, synaptic loss, and progressive neurodegeneration.Customised Model Development
Are developed using iPSC-derived neurons and glia, with genetic editing and co-culture to capture neurodegeneration and disease progression.
The RealBrain® Platform
Our Services - fist listing option
Models for Neurodegenerative Diseases
Alzheimer’s disease (amyloid, tau, synaptic loss)
Disease progression and cellular response
profiling
Neural Network Analysis
Quantification of network dynamics,
formation, maturation, and plasticity in
response to compounds
Biomarker Discovery
Transcriptomic and proteomics, profiling of
neural markers and cellular composition
Mechanism-of-Action Studies
Cell-specific responses - neurons, astrocytes
Ferroptosis and novel cell death pathways
Efficacy Screening
Neuroinflammation profiling
Functional response to test compounds
Safety & Toxicity Profiling
Acute and chronic neurotoxicity
Oxidative stress and viability assessment
High-Content Phenotypic Screening
Multiparametric imaging & AI-based analysis
Dose-response and target prioritisation
Target Validation in Human-Relevant Models
Early-stage testing of lead candidates
Translatable, reproducible data aligned
with regulatory guidance
Key Assays
Cytotoxicity & viability in acute & chronic
conditions
Neural morphology & plasticity assessed through
imaging & markers
Neuroinflammation profiling
Targeted protein profiling of neural markers &
cellular composition
Omics profiling
Our Services - second listing option
Neural Network Analysis: Maturation, network dynamics, plasticity, and compound response
Biomarker Discovery: Transcriptomic and proteomic profiling, cell composition analysis
Mechanism-of-Action Studies: Cell-specific responses, ferroptosis and novel pathways
Efficacy Screening: Functional readouts, inflammation profiling, dose-response
Safety & Toxicity Profiling: Acute/chronic neurotoxicity, oxidative stress, viability
High-Content Screening: AI-based multiparametric imaging and analysis
Target Validation: Human-relevant models, FDA/EMA-aligned reproducible data
Key Assays
Cytotoxicity & viability in acute & chronic
conditions
Neural morphology & plasticity assessed through
imaging & markers
Neuroinflammation profiling
Targeted protein profiling of neural markers &
cellular composition
Omics profiling
Build Better Data with 3D Neural Tissues—Let’s Work Together
Ready to Start Your Study?
Let’s discuss how our end-to-end services can support your next compound screen, biomarker project, or preclinical program.
Our research and development partners
Industry affiliations and corporate development partners
